Intrauterine Insemination (IUI)

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The appropriate number of developing follicles in an IUI cycle is highly dependent on your age and history. Your doctor will be able to set your medication based on this information aiming for the best and safest outcome.

After an IUI, you’ll take medications to help support your pregnancy in the early stages. 

After about two weeks, you’ll come back into the clinic for an HcG pregnancy test. Patients with positive pregnancy test outcomes are followed closely by both their navigator and provider with labs and ultrasounds to ensure the pregnancy is progressing successfully until graduation to their OB/GYN. If your pregnancy test is negative, we’ll schedule a follow-up visit to discuss your options.

Unless instructed otherwise by a doctor, you can return to normal activity immediately following an IUI procedure. It is typical to experience some light spotting and cramping in the days following the procedure. Additionally, it is important to treat your body as though it’s pregnant by avoiding alcohol, drugs, and limiting caffeine.

Implantation typically occurs 6-12 days after an IUI is conducted.

The cost of Intrauterine Insemination (IUI) varies widely depending on factors like location, clinic, fertility medications, and insurance coverage. Compared to other types of fertility treatments, it's one of the cheapest options out there. It's also a fast outpatient procedure.

The IUI procedure is a low-risk fertility treatment, but there are some potential symptoms and side effects to be aware of. Risks associated with IUI include mild discomfort, spotting, infection (rare), ovarian hyperstimulation syndrome (if fertility medications are used), a slightly increased risk of multiple pregnancies, and a small risk of ectopic pregnancy. The success of IUI is not guaranteed, and not all couples achieve pregnancy with this method.

There are a number of factors that can lead to a successful IUI. The success rate of Intrauterine Insemination (IUI) can vary significantly depending on several factors, including the underlying cause of infertility, the age of the woman, the quality of sperm used, and the experience of the healthcare provider performing the procedure. Success rates are typically reported in terms of the likelihood of achieving a pregnancy per cycle of IUI.

On average, the overall success rate for IUI typically ranges from 10% to 20% per cycle. This means that, on average, 10% to 20% of couples will achieve a pregnancy after one cycle of IUI.

There are a few tasks that need to happen in preparation of an IUI procedure:

• Ovulation monitoring: Your doctor may monitor your natural ovulation cycle to schedule your IUI. This might involve an ultrasound and bloodwork to view ovarian follicles and determine the stage of your cycle.
• Semen sample preparation: A semen sample is not only collected, it's also optimized to maximize the chances of successful fertilization. It is washed to remove dead and weak cells, as well as bacteria. It also removes seminal fluid so only the strongest sperm cells are used in the IUI process.
• Optimal timing: As you go through the preparation stages for your IUI procedure, your doctor will schedule the treatment on the optimal timing based on your body and evidence-based best practices. In addition to monitoring your ovulation, the process is also scheduled based on research revealing the best IUI time is the 24- to 36-hour window following the trigger shot.

The process starts by notifying the clinic on the first day of your cycle. Depending on your treatment plan, you typically take a limited course of oral medications that encourage the recruitment and growth of 1-2 dominant follicles. This is followed by a trigger shot to induce ovulation. The timing of the trigger shot is determined by an ultrasound to see and measure the dominant follicles.

A day or two after the trigger shot, you'll come to the fertility clinic for insemination. The sperm sample is collected and processed, which essentially extracts the seminal fluid and only uses healthy sperm cells. Similar to a pap smear, the cervix is visualized using a vaginal speculum and the sperm is inserted through a tube that goes through your cervix into the uterus. The sperm is then deposited. Read more about IUI here .

The difference between IUI and IVF is that IUI inserts washed semen into a uterus in an attempt to fertilize an egg, while IVF creates an embryo in a lab and then transfers it in the uterus where it hopefully implants.

Intrauterine Insemination (IUI) is a process where sperm is placed directly inside a woman’s uterus to facilitate fertilization. IUI is performed to increase the number of sperm that reach the fallopian tubes thereby increasing the chance of fertilization. Read more about IUI here .